|Awarded On||August 18, 2021|
|Title||Rapid Point-of-care Detection of Ovarian Cancer Biomarkers Using a Common Thermometer for Low-Resource Settings|
|Award Mechanism||High Impact/High Risk|
|Institution/Organization||The University of Texas at El Paso|
|Principal Investigator/Program Director||Xiujun Li|
There are 239,000 new cases of ovarian cancer and 140,000 deaths due to ovarian cancer each year worldwide. However, there are no suitable screening modalities for ovarian cancers and repeated imaging and monitoring of CA125 (a biomarker) levels are often needed to triage equivocal ovarian masses. These detection methods, however, lack accuracy for detecting early-stage asymptomatic disease and, as a result, ovarian cancer is typically diagnosed at an advanced stage. Cancer biomarker detection plays a crucial role in early ovarian cancer diagnosis, treatment, and risk assessment, whereas current immunoassay-based detection methods for ovarian cancer biomarkers require costly and bulky instru...