Grant ID RP210116
Awarded On August 18, 2021
Title The Genetic Design and Engineering Center (GDEC): A CPRIT Core Facility
Program Academic Research
Award Mechanism Core Facility Support Awards
Institution/Organization Rice University
Principal Investigator/Program Director Gang Bao
Cancer Sites All Sites
Contracted Amount $4,000,000
Lay Summary

Biological therapies are revolutionizing cancer treatment. These therapies are based on genetically engineered cells, such as those from the human immune system, that are ‘rewired’ to hunt and destroy cancer cells. To advance these therapies for different types of cancers, and to make them safer and more effective, Texas researchers write synthetic DNA programs and introduce them into living cells. However, unlike programming a computer, programming cells requires physically assembling DNA molecules, a process that involves the mixing of very small volumes of liquid in tiny test tubes. This time-consuming process can be greatly accelerated by a DNA assembly infrastructure based on industrial...

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