Grant ID RP180288
Awarded On February 21, 2018
Title Innate Immune Regulation of Cancer Cell Proliferation
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The University of Texas Southwestern Medical Center
Principal Investigator/Program Director Nan Yan
Cancer Sites Lung and Bronchus, Skin
Contracted Amount $900,000
Lay Summary

Innate Immune Regulation of Cancer Cell Proliferation Nan Yan, Associate Professor, Department of Immunology, UT Southwestern Medical Center. Our immune system responds to viral infection by turning on innate immunity that acts immediately inside of infected (‘sick’) cells and adaptive immunity that brings in T cells and B cells that can better control the infection. Cancer cells can also be detected by the immune system as ‘sick’ cells due to their rapid growth. Unfortunately, many viruses still cause diseases because they can block our immune response. Similarly, many cancers also weaken the immune response around them. One of the most promising strategies to treat cancer is to restore ou...

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