Grant ID RP180178
Awarded On February 21, 2018
Title Imaging glucose stimulated zinc secretion (GSZS) from the prostate by MRI: A potentially powerful method for early detection of prostate cancer
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The University of Texas Southwestern Medical Center
Principal Investigator/Program Director Dean Sherry
Cancer Sites Prostate
Contracted Amount $900,000
Lay Summary

Prostate cancer (PCa) accounts for 33% of all newly diagnosed malignancies and is the second most common cause of death among men in the United States. Screening for PCa commonly consists of a measure of plasma prostate specific antigen (PSA) and a digital rectal exam (DRE). In the current era of widespread PSA testing, ~75% of all prostate cancer cases are detected as a result of abnormal PSA findings but the test remains controversial as it is unclear whether the benefits of early detection by PSA outweigh the risks of misdiagnosis. Benign prostatic hyperplasia (BPH), inflammation, and age can all affect PSA levels. When a PSA test reveals an abnormally high level, clinicians often orde...

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