Grant ID RP180140
Awarded On February 21, 2018
Title EXTernal beam radiation to Eliminate Nominal metastatic Disease (EXTEND): A randomized phase II basket trial to assess local control of oligometastatic disease
Program Academic Research
Award Mechanism Individual Investigator Research Awards for Clinical Translation
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Chad Tang
Cancer Sites All Sites
Contracted Amount $2,394,412
Lay Summary

Cancers that have spread to organs away from their original location are labelled as “metastatic” and have generally been considered universally fatal. A diagnosis of metastatic cancer usually means treatment that is conservative, palliating symptoms and/or extending life moderately, but not curing patients. This paradigm was originally developed in the early days of cancer treatment and has generally changed little. However, with improvements in our ability to treat and diagnose, we are starting to understand that not all metastatic cancers should be considered equal. That some patients with metastatic cancer have disease spread only to a few additional organs. We have begun labeling those ...

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