Grant ID RP170691
Awarded On August 16, 2017
Title Patient-Derived Xenograft and Advanced in Vivo Models (PDX-AIM) Core Facility
Program Academic Research
Award Mechanism Core Facility Support Awards
Institution/Organization Baylor College of Medicine
Principal Investigator/Program Director Michael Lewis
Cancer Sites All Sites
Contracted Amount $4,766,430
Lay Summary

With a few exceptions, traditional cancer research using tumor-derived cell lines grown on plastic have failed to yield results that benefit cancer patients. There are many reasons for this failure. To circumvent these shortcomings, researchers have begun to use “patient-derived xenografts” (PDX), and other models in which human tumors are grown in living hosts, including the mouse and the fertilized chicken egg. Development of a Patient-Derived Xenograft and Advanced In Vivo Models (PDX-AIM) Core is a high priority for Baylor College of Medicine (BCM) and its affiliate, The Texas Children’s Hospital (TCH). BCM established a new PDX-AIM Core in 2016 jointly backed by the BCM Advanced Technol...

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