Grant ID RP170387
Awarded On November 16, 2016
Title Development and Validation of a Network-guided, Multi-objective Optimization Model for Cancer Data Analysis.
Program Academic Research
Award Mechanism Individual Investigator Research Awards for Computational Biology
Institution/Organization Baylor College of Medicine
Principal Investigator/Program Director Zhandong Liu
Cancer Sites All Sites
Contracted Amount $889,679
Lay Summary

Chemotherapy is the most frequently used treatment in cancer. Although it has been shown to be effective in treating some cancers, a great spectrum of variation has been observed in the ability of chemotherapy to treat solid human cancers. Identifying key pathways that determine not only response to treatment but also survival is a critical step toward developing effective personalized cancer treatments. Massive amounts of genomic, molecular, and clinical data has been generated in recent years with the goal of comprehensively characterizing human cancers. However, integration and analysis of this data is currently limited by its sheer size and complexity. To address this challenge, we ha...

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