Grant ID RP160716
Awarded On May 18, 2016
Title Texas Pediatric Patient Derived Xenograft Facility
Program Academic Research
Award Mechanism Core Facility Support Awards
Institution/Organization The University of Texas Health Science Center at San Antonio
Principal Investigator/Program Director Peter J Houghton
Cancer Sites All Sites
Contracted Amount $5,079,843
Lay Summary

Despite advances in treating childhood cancer, there is a long way to go before the cure rates and the long-term consequences of therapy are acceptable. Developing more effective agents for those children not currently cured, and less toxic therapy to others, poses significant challenges. Additionally, some minority and underserved populations – such as Hispanic populations common across Texas – have outcomes that are worse than the general population, and these populations may be poorly represented in the few clinical trials that are available. To overcome these challenges, we will develop and validate preclinical models that represent the genetic diversity of childhood cancer from the pop...

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