Grant ID RP160384
Awarded On November 19, 2015
Title Promoting The Functions of Memory T cells for Adoptive T cell Therapy
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The Methodist Hospital Research Institute
Principal Investigator/Program Director Jin Wang
Cancer Sites All Sites
Contracted Amount $840,505.26
Award Transfer Information

Previous Organization: Baylor College of Medicine

Expended at Previous Organization: $47,170.74

Lay Summary

Vaccines have been successful in protecting humans against infection by many deadly pathogens. The cell types generated after vaccination and responsible for the protection are called immune memory cells. After re-encountering the same pathogens, the immune memory cells can mount robust immune responses to attack the pathogens, thereby protecting us from future infections. Based on the success of vaccination against pathogens, vaccines have been used to immunize patients with components present in tumor but not normal tissues. The patients would generate immune memory cells against cancer. Due to limited number of memory T cells generated in the patients, activating immune cells with tumo...

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