Allterum Therapeutics, a Houston, TX based company, is developing a new drug for the treatment of pediatric T-cell acute lymphoblastic leukemia – a common form of childhood cancer. Although current treatments are effective for a majority of children with this disease, approximately 20% of patients experience a recurrence of the disease. Unfortunately, no drugs exist to effectively help patients who experience this relapse.

Our drug is an antibody which is able to much more specifically target and kill cancer cells without the broader side-effects typically observed with conventional chemotherapies. Therefore, Allterum Therapeutics is addressing a major unmet medical need, as our drug is expe...

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Allterum Therapeutics, a Houston, TX based company, is developing a new drug for the treatment of pediatric T-cell acute lymphoblastic leukemia – a common form of childhood cancer. Although current treatments are effective for a majority of children with this disease, approximately 20% of patients experience a recurrence of the disease. Unfortunately, no drugs exist to effectively help patients who experience this relapse.

Our drug is an antibody which is able to much more specifically target and kill cancer cells without the broader side-effects typically observed with conventional chemotherapies. Therefore, Allterum Therapeutics is addressing a major unmet medical need, as our drug is expected to be effective not only in children with recurring leukemia, but could also be used to aid conventional chemotherapies when patients are first treated. Our technology fits within CPRIT’s mission as we are developing a new agent for the treatment of cancer. Furthermore, our research will help further the scientific community’s understanding of pediatric leukemias and the ability of targeted therapies to aid conventional chemotherapies to elicit a better patient response, and to hopefully result in a better prognosis for patients and their families.

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