John Paul Shen, M.D.
John Paul Shen, M.D.
The University of Texas MD Anderson Cancer Center
Titles & Positions

  • Assistant Professor, Department of Gastrointestinal (GI) Medical Oncology, Division of Cancer Medicine

Institutional & Related Links



Grant Information

Grant ID: RR180035
Grant Mechanism: 
Recruitment of First-Time, Tenure-Track Faculty Members
Recruited From: 
University of California, San Diego
Date Awarded: 
May 16, 2018
Grant Amount: 

Modern genomic sequencing techniques reveal that cancers come with a bewildering variety of mutations. Cancers that have the same driving mutation but grow in different environments — skin vs. colon, for example — may respond completely differently to the same therapy.

Conversely, tumors growing in different patients in the same organ may superficially appear similar but are often genetically diverse. With little information about how a tumor will respond to treatment except trial and error, it is challenging for oncologists to identify the optimal therapy for each patient.

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