|Awarded On||August 18, 2021|
|Title||The GCC Microphysiological Lead Optimization and Toxicity Screening facility|
|Award Mechanism||Core Facility Support Awards|
|Institution/Organization||Texas A&M University System Health Science Center|
|Principal Investigator/Program Director||Clifford C Stephan|
|Cancer Sites||All Sites|
The Gulf Coast Consortium (GCC) Microphysiological Lead Optimization Screening facility (MLOTS) is a new multi-institutional drug discovery core designed to accelerate the development of new cancer therapies. MLOTS responds to the need of cancer researchers for specialized facilities to rapidly and efficiently evaluate new drugs and drug combinations that may be safe and effective cancer treatments for cancer patients. To achieve its goals, MLOTS provides access to sophisticated 3D testing systems that replicate in the test tube the complicated environment seen by tumors. MLOTS will also use models of normal liver, heart and the brain to test whether the new drugs have toxicities that could ...