Grant ID DP190066
Awarded On August 21, 2019
Title Tumor specific T-cell activating cancer vaccines for immunotherapy of solid tumors including HPV
Program Product Development Research
Award Mechanism Texas Company Product Development Awards
Institution/Organization OncoNano Medicine
Principal Investigator/Program Director Kartik Krishnan
Cancer Sites Cervix Uteri, Head and Neck, Penis
Contracted Amount $15,427,699
Lay Summary

OncoNano Medicine, Inc., a spinout of UT Southwestern that is headquartered in Southlake, TX, is developing a nanovaccine immunotherapeutic for human papilloma virus (HPV)-induced cervical cancer, head and neck cancer, and anogenital cancers. OncoNano’s technology is a proprietary, polymer-based, pH-sensitive micelle that delivers an antigen to the lymph nodes, while also activating the stimulator of interferon genes (STING) pathway, resulting in a cancer-specific patient immune response. Cervical cancer is one of the leading causes of cancer mortality among women, and more than 270,000 deaths occur from cervical cancer each year worldwide. With this urgent need, OncoNano’s unique approach t...

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